Nanostructured hybrid materials for bone-tooth unit regeneration

Magnesium-containing nanostructured hybrid scaffolds for enhanced dentin regeneration.

Dental caries is one of the most prevalent chronic diseases in the United States, affecting 92% of adults aged 20-64 years. Scaffold-based tissue engineering represents a promising strategy to replace damaged dental structures and restore their biological functions. Current single-component scaffolding materials used for dental tissue regeneration, however, cannot provide the proper microenviro...

Bone and Tooth Regeneration in Maxillofacial Region

1Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan 2USAA Foundation, College of Engineering, The University of Texas at San Antonio, San Antonio, TX 78249, USA 3Department of Oral and Maxillofacial Surgery, Center of Operative Medicine II, Heinrich Heine University, 40225 Düsseldorf, Germany 4Forensic Odontology, Melbourne Dental ...

Hybrid nanostructured materials for high-performance electrochemical capacitors

Promoting bioengineered tooth innervation using nanostructured and hybrid scaffolds.

The innervation of teeth mediated by axons originating from the trigeminal ganglia is essential for their function and protection. Immunosuppressive therapy using Cyclosporine A (CsA) was found to accelerate the innervation of transplanted tissues and particularly that of bioengineered teeth. To avoid the CsA side effects, we report in this study the preparation of CsA loaded poly(lactic-co-gly...

Nanostructured Biomaterials for Regeneration.

Biomaterials play a pivotal role in regenerative medicine, which aims to regenerate and replace lost/dysfunctional tissues or organs. Biomaterials (scaffolds) serve as temporary 3D substrates to guide neo tissue formation and organization. It is often beneficial for a scaffolding material to mimic the characteristics of extracellular matrix (ECM) at the nanometer scale and to induce certain nat...